Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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5,056 – 5,070 of 60,541 results

5,056

Cayman Chemical Nazartinib, Purity: ≥98%, CAS: 1508250-71-2, 25 mg

An inhibitor of mutant EGFRs; selective for EGFR mutant cell lines, including H3255 and HCC827 lung adenocarcinoma cells (IC50s = 6.11 and 1.52 nM, respectively) and resistant H1975 NSCLC cells (IC50 = 4.18 nM), over cells expressing wild-type EGFR (IC50 = 160.6 nM for HaCaT keratinocytes); decreases phosphorylation of EGFR in H3255, HCC827, and H1975 cells (EC50s = 5, 1, and 3 nM) and inhibits cell proliferation of H3255, HCC827, and H1975 cells (EC50s = 9, 11, and 25 nM) but does not affect cell proliferation in cell lines containing wild-type EGFR; reduces tumor growth in an HCC827 lung adenocarcinoma mouse xenograft model at doses ranging from 3 to 100 mg/kg per day

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5,057

Medchemexpress LLC HY-18312 5mg , PF-4618433 CAS:1166393-85-6 Purity:>98%

HY-18312 5mg PF-4618433 CAS: 1166393-85-6 PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. PF-4618433 may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects and for targeted bone regeneration. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,058

Medchemexpress LLC 2'-Deoxy-5,N4-dimethylcytidine | 25406-44-4 | MFCD10566733 | C11H17N3O4 | 5 MG

2'-Deoxy-5,N4-dimethylcytidine is a purine nucleoside analog. It targets nucleoside antimetabolites/analogs and is primarily utilized in cancer research.

Purine nucleoside analog
Targets nucleoside antimetabolites/analogs
Utilized in cancer research

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5,059

Medchemexpress LLC 1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester | 903550-26-5 | MFCD09037501 | 278.16 | 500 G

1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester is a biochemical reagent for life science related research. This organic compound can be used as a biological material.

Biochemical reagent
Biological material or organic compound
For life science related research
For research use only

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5,060

Cayman Chemical DU-14, Purity: ≥95%, CAS: 186303-55-9, 5 mg

A steroid sulfatase inhibitor (IC50 = 55.8 nM); inhibits the proliferation of MCF-7 breast cancer cells (IC50 = 38.7 nM); potentiates DHEAS reversal of scopolamine-induced amnesia in the passive avoidance test in rats at 30 mg/kg; prevents scopolamine-induced amnesia in the passive avoidance test in rats at 30 mg/kg per day

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5,061

Medchemexpress LLC Pf-794 | 2056111-45-4 | 99.2% | 100 MG

Pf-794 is a small-molecule research compound that functions as a selective, ATP-competitive inhibitor of Traf2- and Nck-interacting kinase (TNIK). It is supplied for laboratory research and preclinical studies.

Targets Traf2- and Nck-interacting kinase (TNIK).
ATP-competitive mechanism of inhibition.
Reported high purity for reliable experimental use.
Available in small research pack sizes commonly 100 mg.
CAS number 2056111-45-4 for unambiguous identification.

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5,062

Cayman Chemical 1,3-Didocosahexaenoyl-2-Palmitoyl Glycerol, Purity: ≥98%, CAS: 197016-86-7, 5 mg

A triacylglycerol; has been found in higher amounts than PDD in the Steller sea lion meat and harp seal oil and at lower amounts than PDD in the meat of a variety of fishes

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5,063

Medchemexpress LLC Delta-tocotrienol | 25612-59-3 | 98.1% | 10 MG

Delta-tocotrienol is a vitamin E family compound used as an analytical standard and research reagent with antioxidant and lipid-modulating activity. It is supplied as a high-purity reference material for laboratory assays.

CAS number 25612-59-3.
IUPAC name (2R)-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol.
Molecular formula C27H40O2.
Molecular weight 396.6 g/mol.
Purity 98.1%.
Provided as a 10 mg solid vial for analytical use.

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5,064

Medchemexpress LLC Tyrosylleucine | 17355-10-1 | 99.9% | 25 MG

Tyrosylleucine (Tyr-Leu, YL) is an orally active dipeptide reported to exhibit potent antidepressant-like activity. It is supplied as a high-purity research-grade compound for preclinical in vitro and in vivo studies.

Sequence Tyr-Leu dipeptide
Chemical formula C15H22N2O4, molecular weight 294.35 g·mol⁻¹
High purity (99.9% by HPLC)
Supplied in milligram quantities suitable for research use
Stable as a solid when stored under recommended conditions

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5,065

Cayman Chemical 1,2-Dioleoyl-3-Myristoyl-rac-glycerol, Purity: ≥98%, CAS: 35804-98-9, 5 mg

A triacylglycerol; has been found in the fat body of male B. lapidarius bumblebees and in R. erythropolis bacteria utilizing phenol or succinic acid as a carbon source

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5,066

Cayman Chemical ANTIBODY 22-HDHA 100ug

An oxidation product of DHA; formed by human CYP4F3B in BTI-TN-5B1-4 microsomes; serum levels increase in humans following dietary DHA supplementation

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5,067

Cayman Chemical Danoprevir, Purity: ≥95%, CAS: 850876-88-9, 5 mg

An HCV NS3/4A protease inhibitor (IC50 = 1 nM); selective for NS3/4A over a panel of 53 proteases (10 μM); inhibits replication of the HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s = 0.2-0.4 nM) as well as 2b and 3a (IC50s = 1.6 and 3.5 nM, respectively) in vitro; reduces the number of HCV genotype 1b replicons in Huh-7 cells (EC50 = 1.8 nM)

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5,068

Medchemexpress LLC 8-Nonynoic acid | 30964-01-3 | 154.21 | 1 G

8-Nonynoic acid is a fatty acid that belongs to the group of octynoic acids. It exhibits antibacterial activity against gram-positive bacteria by binding to bacterial fatty acids, and inhibits the growth of gram-negative bacteria by inhibiting fatty acid synthesis. This compound is also capable of inhibiting the growth of both aerobic and anaerobic bacteria in biochemical assays.

Exhibits antibacterial activity against gram-positive bacteria.
Inhibits growth of gram-negative bacteria by inhibiting fatty acid synthesis.
Inhibits growth of both aerobic and anaerobic bacteria.

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5,069

Medchemexpress LLC (E)-3-(3-phenyl-2,1-benzoxazol-5-yl)prop-2-enoic acid | 2967648-66-2 | 99.7% | 5 MG

IP6K2-IN-2 is a small-molecule inhibitor of inositol hexakisphosphate kinase 2 (IP6K2) with submicromolar activity. It inhibits IP6K2 (IC50 0.58 μM), IP6K1 (IC50 0.86 μM), and IP6K3 (IC50 3.08 μM). The compound is supplied with high purity and is used as a research tool in studies of metabolic regulation and obesity.

Selective inhibitor of IP6K2 with submicromolar potency.
Reported activity against related isoforms IP6K1 and IP6K3.
High purity suitable for biochemical and cellular assays.
Soluble in DMSO (approx. 25 mg/mL) for solution-based assays.
Available as solid and as prepared DMSO solution for assay flexibility.
Storage recommendations: powder at -20°C; solutions at -80°C for long-term stability.
Intended for research use in metabolic and obesity-related studies.

Pricing & Availability

5,070

eMolecules 1404436-51-6 | Medchem Express | LYP-IN-1 | 5mg | 713705496 | HY-108944 | 501.92 | C28H20ClNO6

Ambeed | (S)-4-Benzyl-2-(4-(trifluoromethyl)pyridin-2-yl)-45-dihydrooxazole | 100mg | 633660029 | A1258482 | 1831829-87-8 | 306.288 | C16H13F3N2O

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Bioactive Small Molecules

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Medchemexpress LLC HY-18312 5mg , PF-4618433 CAS:1166393-85-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2'-Deoxy-5,N4-dimethylcytidine | 25406-44-4 | MFCD10566733 | C11H17N3O4 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester | 903550-26-5 | MFCD09037501 | 278.16 | 500 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pf-794 | 2056111-45-4 | 99.2% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Delta-tocotrienol | 25612-59-3 | 98.1% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tyrosylleucine | 17355-10-1 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 8-Nonynoic acid | 30964-01-3 | 154.21 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (E)-3-(3-phenyl-2,1-benzoxazol-5-yl)prop-2-enoic acid | 2967648-66-2 | 99.7% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More